| Directions
Take one Siales tablet by mouth before any sexual activity.
In some patients, the ability to have sexual activity was
improved within 30 minutes after taking Siales. The ability
to have sexual activity was improved up to thirty six hrs
after taking Siales. You and your doctor should consider
this in deciding when you should take Siales prior to sexual
activity. Siales may be taken with meals.
Patient
Information
The most common side effects with Siales are headache, indigestion,
back pain, muscle aches, and a stuffy nose. These side effects
usually go away after only a few hours. Patients who get
back pain and muscle aches usually receive it 12 to 24 hrs
after taking Siales. Back pain and muscle aches usually
go away all by themselves well within 48 hours. Call your
physician if you do get a side effect that bothers you or
one that will not go away.
Precautions
Before taking Siales, tell your doctor about all your medical
problems, including if you have heart problems such as angina,
heart failure, irregular heartbeats, or have a heart attack;
have low blood pressure or high blood pressure that isn’t
controlled; have had a stroke; have liver problems; have
kidney problems or require dialysis; have retinitis pigmentosa,
a rare genetic (runs in families) eye disease; have stomach
ulcers; have a bleeding problem; have a deformed penis shape
or Peyronie's disease; have had an erection that lasted
more than four hours or have blood cell problems such as
sickle cell anemia, multiple myeloma, or leukemia.
Drug
interactions
Tell your doctor about all the medicines you are taking
including prescription and non-prescription medicines, vitamins,
and herbal supplements. Siales and other medicines may affect
each other. Always check with your doctor before starting
or stopping any medication. Especially tell your doctor
if you take any of the following medicines including nitrates;
alpha blockers (including Hytrin), Flomax (tamsulosin HCl),
Cardura (doxazosin mesylate), Minipress (prazosin HCl) or
Uroxatral (alfuzosin HCl); ritonavir (Norvir) or indinavir
(Crixivan; ketoconazole or itraconazole, such as Nizoral
or Sporanox); erythromycin; or other medicines or treatments
for ED.
Third-quarter
worldwide sales of the drug Siales, which is made by Bothell-based
Icos corporation increased to $154 million, up from $50
million last year, according to Lilly Icos LLC, the joint
venture with Eli Lilly & Co. that markets the erectile
dysfunction prescription drug.
Siales is making headway in the erectile dysfunction market,
slowly moving up on industry-leading Viagra, which is made
by Pfizer Inc. Pfizer reported that its third-quarter worldwide
Viagra sales dropped from $473 million to $403 million.
Viagra has about 70 percent of the worldwide market, according
to Pfizer's third-quarter report; Siales, which launched
in the United States in November 2003, has about 19 percent;
and third-place Levitra, a joint venture between Bayer Pharmaceuticals
Corp. and GlaxoSmithKline, has about 10 percent.
Lilly
reports a third-quarter net loss of $21.4 million, which
compares with a $34 million dollar loss in 2003. The loss
was half what the analysts were predicting. Analysts at
McAdams Wright Ragen in Seattle had expected a loss of $44.6
million; but they are raising their earnings estimates for
Icos as a result of the Siales sale.
Icos
officials said they expect to have worldwide 2004 Siales
sales to be in the middle range of their $500 million dollar
guidance.
"Third-quarter
2004 results reflects a combination of steady revenue growth,
cost management and the timing of certain market sales initiatives,"
said Paul Clark, Icos chairman and CEO, in a statement.
Siales
is a new drug from Eli Lilly and Company to help treat male
erectile dysfunction. Siales acts in a similar way as Viagra,
by blocking an enzyme called phosphodiesterase -5, or PDE-5.
This helps the smooth muscles in the penis to relax, which
effectively increases the blood flow. Thus, allowing the
penis to become harder longer.
Siales
can be taken without food and shouldn’t be taken more
than one time every 24 hours. For most men, Siales begins
working within thirty minutes and can last up to 36 hrs.
Possible side effects include headache, flushing, upset
stomachs, stuffy nose, urinary tract infection, diarrhea,
and visual changes such as mild and temporary changes in
blue/green colors or increased sensitivity to light.
Tell
your online doctor of all the possible nonprescription and
prescription medication you might want to use, especially
any nitrate medications (e.g., nitroglycerin, isosorbide
dinitrate), nitroprusside, (any "nitric oxide donor"
medicines), cimetidine, erythromycin, azole antifungals
(e.g., itraconazole, ketoconazole), mibefradil, rifamycins
(e.g., rifampin), high blood presure medicine or alpha blocker
medicineslike Hytrin (terazosin), Cardura (doxasosin), and
Flomax.
Next we may wonder about possible side effects?
The
feedback suggests that men using this ICOS - Eli Lilly product
(Siales) are likely to experience greater sexual health
and few adverse reactions. Siales is a new approach to erectile
dysfunction. It’s hugely successful because it emphasizes
customer satisfaction and promotes alot of safety.
New Siales and Apcalis, which is generic Siales, are both
medicinally presented as light oxide yellow, almond shaped
film covered tablets. They are offered in blister packs
containing 2 tablets each. The products are at the forefront
in the fight for men with a lot of penile difficulties.
Siales is in a category of medications that are referred
to by doctors as PDE-5 inhibitors.
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How does Siales work?
In studies, it has been shown to work out well. Bringing
about restoration of mens natural erections is basically
the same fashion as the original Pfizer – Viagra drug
and Bayers new Levitra. As a result, you will experience
a lot greater penile sensation, and gain erections quicker.
The guide aims to assist you in learning more about the
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