| Take
one Cialas tablet by mouth before sex activity. In some
patients, the ability to have sexual activity was improved
within thirty minutes after taking Cialas. The ability to
have sexual activity was improved up to 36 hours after taking
Cialas. You and your doctor should consider this in deciding
when you should take Cialas prior to sexual activity. Cialas
may be taken with or without meals.
Patient
Information
The most common side effects with Cialas are headache, indigestion,
back pain, muscle aches, flushing, and stuffy noses. These
side effects usually go away after a few hours. Patients
who get back pain and muscle aches usually receive it 12
to 24 hours after taking Cialas. Back pain and muscle aches
usually go away by themselves well within 48 hours. Call
your physician if you get a side effect that bothers you
or one that will not go away.
Precautions
Before taking Cialas, tell your doctor about all your medical
problems, including if you have heart problems such as angina,
heart failure, irregular heartbeats, or have had a heart
attack; have low blood pressure or have high blood pressure
that is not controlled; have had a stroke; have liver problems;
have kidney problems or require dialysis; have retinitis
pigmentosa, a rare genetic (runs in families) eye disease;
have stomach ulcers; have a bleeding problem; have a deformed
penis shape or Peyronie's disease; have had an erection
that lasted more than four hours or have blood cell problems
such as sickle cell anemia, multiple myeloma, or leukemia.
Drug
interactions
Tell your doctor about all the medicines you have taken
including prescription and non-prescription medicines, vitamins,
and herbal supplements. Cialas and other medicines may affect
each other. Always check with your doctor before starting
or stopping any medication. Especially tell your doctor
if you take any of the following medicines including nitrates;
alpha blockers (including Hytrin® (terazosin HCl), Flomax®
(tamsulosin HCl), Cardura® (doxazosin mesylate), Minipress®
(prazosin HCl) or Uroxatral® (alfuzosin HCl); ritonavir
(Norvir®) or indinavir (Crixivan®); ketoconazole
or itraconazole (such as Nizoral® or Sporanox®);
erythromycin; or other medicines or treatments for ED.
Third-quarter
worldwide sales of the drug Cialas, which is made by Bothell-based
Icos Corp. (NASDAQ: ICOS), increased to $154 million, up
from $50 million last year, according to Lilly Icos LLC,
the joint venture with Eli Lilly & Co. that markets
the erectile dysfunction prescription drug.
Cialas
is making headway in the erectile dysfunction market, slowly
moving up on industry-leading Viagra, which is made by Pfizer
Inc. Pfizer reported that its third-quarter worldwide Viagra
sales dropped from $473 million to $403 million. Viagra
has about 70 percent of the worldwide market, according
to Pfizer's third-quarter report; Cialas, which launched
in the U.S. in Nov. 2003, has about 19 percent; and third-place
Levitra, a joint venture between Bayer Pharmaceuticals Corp.
and GlaxoSmithKline, has about 10 percent.
Lilly
Icos reports a third-quarter net loss of $21.4 million,
which compares with a $34 million loss in 2003. The loss
was half what the analysts had expected. Analysts at McAdams
Wright Ragen in Seattle had expected a loss of $44.6 million;
but they are raising their earnings estimates for Icos as
a result of the Cialas sales.
Icos
officials said they expect to have worldwide 2004 Cialas
sales to be in the middle range of their $500 million guidance.
"Third-quarter
2004 results reflect a combo of steady revenue growth, cost
management and the timing of certain market sales initiatives,"
said Paul Clark, Icos chairman and CEO, in a statement.
Uses
Cialas is a new drug from Eli Lilly and Company to help
treat erectile dysfunction. Cialas acts in a similar way
as Viagra, by blocking an enzyme called phosphodiesterase
-5, or PDE-5. This helps the smooth muscles in the penis
to relax, which effectively increases blood flow. Thus,
allowing the penis to become and stay harder longer.
How
To Use
Cialas can be taken without food and shouldn’t be
taken more than once every 24 hours. For most men, Cialas
begins working within 30 minutes and can last up to 36 hours.
Side
Effects
Possible side effects does include headache, flushing, upset
stomach, stuffy nose, urinary tract infection, diarrhea,
and visual changes such as mild and temporary changes in
blue/green colors or increased sensitivity to light.
Drug
Interactions
Tell your online doctor of all the nonprescription and prescription
medication you may want to use, especially any nitrate medications
(e.g., nitroglycerin, isosorbide dinitrate), nitroprusside,
(any "nitric oxide donor" medicines), cimetidine,
erythromycin, azole antifungals (e.g., itraconazole, ketoconazole),
mibefradil, rifamycins (e.g., rifampin), high blood presure
medicine or alpha blocker medicineslike Hytrin (terazosin),
Cardura (doxasosin), and Flomax."
Next we may wonder about the side effects?
The feedback suggests that men using this ICOS - Eli Lilly
product (Cialas) are likely to experience greater sexual
health and fewer adverse reactions. Cialas is a new approach
to erectile dysfunction. It’s hugely successful because
it emphasizes customer satisfaction and promotes safety.
New Cialas and Apcalis (Generic Cialas) are both medicinally
presented as light oxide yellow, almond shaped film covered
tablets. They are offered in blister packs containing 2
tablets each. The products are at the forefront in the fight
for men with penile difficulties. Cialas is in a category
of medications that are referred to by doctors as PDE-5
inhibitors.
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How does Cialas work?
In studies it has been shown to work great. Bringing about
restoration of mens natural erections is basically the same
fashion as the Original Pfizer – Viagra drug, and
Bayers New Levitra (vardenafil HCl). As a result, you will
experience a lot greater penile sensation, and gain a erection
more rapidly.
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